Top South Carolina Nursing Schools and Programs of 2025 & 2026

Looking ahead to 2030, the U.S. Department of Health and Human Services anticipates a shortage of 10,400 nurses in South Carolina.
With 25 fully-accredited nursing schools in the state and additional programs seeking approval, the task of selecting the most suitable option becomes pivotal.
As the nursing deficit is projected to reach 10,000 by 2030, it is crucial to explore the top nursing programs in South Carolina that can equip individuals to meet this growing demand.
This comprehensive guide delves into the premier nursing programs in South Carolina, providing insights into salary and employment prospects while also addressing the process of obtaining a South Carolina nursing license.

Continue reading to gain valuable information on the journey to becoming a nurse in South Carolina, or navigate directly to our curated lists featuring the best nursing schools or the finest nurse practitioner (NP) programs in the state.

The Best Nursing Schools in South Carolina

Whether aspiring for a two-year associate degree in nursing (ADN), a four-year bachelor of science in nursing (BSN), or a graduate degree in nursing, South Carolina offers a diverse array of nursing programs tailored to individual career goals.

1. University of South Carolina College of Nursing

• Location: Columbia, SC
• Website: https://www.sc.edu/study/colleges_schools/nursing/
• Description: The University of South Carolina College of Nursing offers a comprehensive and rigorous nursing program at both the undergraduate and graduate levels. The BSN program is designed to prepare students for professional nursing practice with a combination of classroom instruction, simulation labs, and clinical placements in diverse healthcare settings. USC also offers an RN-to-BSN program, as well as advanced practice options at the master’s level, including specialties in nurse practitioner, nurse anesthesia, and nursing leadership. The school is committed to providing evidence-based, culturally competent care and offers opportunities for students to engage in innovative research. USC’s faculty are recognized experts in their fields, and the college has strong ties to healthcare organizations across the state, providing students with valuable hands-on experience.
• Accreditation: CCNE
• Tuition: Approx. $12,000 per year (in-state undergrad)
• Programs: BSN, RN-to-BSN, MSN, DNP
• Online Options: Yes (RN-to-BSN, some MSN tracks)

2. Clemson University School of Nursing

• Location: Clemson, SC
• Website: https://www.clemson.edu/academics/degrees/nursing-bs.html
• Description: Clemson University offers an accredited Bachelor of Science in Nursing (BSN) program, which provides students with a strong foundation in nursing practice, critical thinking, and compassionate care. The program integrates clinical practice with evidence-based instruction and features state-of-the-art simulation labs to help students develop clinical skills. Clemson also offers an RN-to-BSN program for registered nurses looking to further their education and broaden their career opportunities. The university’s nursing faculty are dedicated to providing high-quality education and mentorship, ensuring that students graduate well-prepared for the workforce. Clemson is known for its emphasis on research and leadership in healthcare, with students having opportunities to engage in various research projects and community outreach programs.
• Accreditation: CCNE
• Tuition: Approx. $15,000 per year (in-state undergrad)
• Programs: BSN, RN-to-BSN
• Online Options: Yes (RN-to-BSN program)

3. Charleston Southern University School of Nursing

• Location: Charleston, SC
• Website: https://www.csuniv.edu/academics/nursing
• Description: Charleston Southern University offers a dynamic nursing program that prepares students for professional nursing careers in a variety of healthcare settings. The BSN program emphasizes holistic care, clinical practice, and the development of leadership skills, with a focus on meeting the healthcare needs of diverse populations. CSU’s nursing students benefit from a combination of classroom instruction, hands-on clinical experience, and exposure to real-world healthcare environments. The university also offers an RN-to-BSN program for registered nurses who wish to complete their bachelor’s degree. Charleston Southern provides students with a strong Christian-based education and encourages the development of compassionate, ethical, and competent nurses.
• Accreditation: CCNE
• Tuition: Approx. $18,000 per year (undergrad)
• Programs: BSN, RN-to-BSN
• Online Options: Yes (RN-to-BSN program)

4. Medical University of South Carolina College of Nursing

• Location: Charleston, SC
• Website: https://education.musc.edu/departments/nursing
• Description: The Medical University of South Carolina (MUSC) College of Nursing is one of the leading nursing schools in the state and is highly regarded for its commitment to nursing education, research, and practice. The BSN program at MUSC prepares students to be compassionate, skilled nurses, with a strong emphasis on evidence-based practice, leadership, and patient-centered care. MUSC also offers advanced practice programs at the master’s and doctoral levels, including nurse practitioner and nurse anesthesia specialties. The RN-to-BSN program allows registered nurses to complete their bachelor’s degree online while working, offering a flexible learning schedule. MUSC has strong clinical affiliations with hospitals and healthcare organizations in the region, ensuring students have opportunities for practical, hands-on learning.

Accreditation: CCNE

• Tuition: Approx. $14,000 per year (in-state undergrad)
• Programs: BSN, RN-to-BSN, MSN, DNP
• Online Options: Yes (RN-to-BSN program, some MSN tracks)

5. Piedmont Technical College School of Nursing

• Location: Greenwood, SC
• Website: https://www.ptc.edu/nursing
• Description: Piedmont Technical College offers an Associate Degree in Nursing (ADN) program that prepares students for entry-level nursing practice. The program is known for its affordable tuition and its commitment to providing students with hands-on clinical training in local healthcare facilities. The ADN program is ideal for students who wish to become registered nurses and enter the workforce quickly. Piedmont Technical College also offers an RN-to-BSN program in partnership with other universities in South Carolina, providing a seamless transition for RNs who wish to further their education. The program is focused on preparing nurses to provide high-quality care, improve patient outcomes, and work as part of a healthcare team.
• Accreditation: ACEN
• Tuition: Approx. $4,000 per year (in-state undergrad)
• Programs: ADN, RN-to-BSN (in partnership with other universities)
• Online Options: Yes (RN-to-BSN program)

6. Anderson University College of Nursing and Public Health

• Location: Anderson, SC
• Website: https://www.andersonuniversity.edu/nursing
• Description: Anderson University’s College of Nursing and Public Health offers a nursing program that blends traditional classroom learning with hands-on clinical experience. The university’s BSN program focuses on developing students into critical thinkers, compassionate caregivers, and skilled professionals. Anderson University emphasizes a holistic approach to nursing, which includes a strong foundation in ethics, healthcare delivery, and community health. The school offers an RN-to-BSN program for registered nurses who want to advance their education. The College of Nursing and Public Health is committed to addressing the healthcare needs of South Carolina’s diverse populations and preparing students for leadership roles in nursing practice.
• Accreditation: CCNE
• Tuition: Approx. $24,000 per year (undergrad)
• Programs: BSN, RN-to-BSN
• Online Options: Yes (RN-to-BSN program)

7. North Greenville University School of Nursing

• Location: Tigerville, SC
• Website: https://www.ngu.edu/nursing.php
• Description: North Greenville University offers a Bachelor of Science in Nursing (BSN) program that provides students with the knowledge and clinical experience needed to become skilled and compassionate registered nurses. The program emphasizes Christian values, with students learning to care for patients in a holistic manner. The curriculum includes clinical practice in a variety of settings, from hospitals to community health environments. North Greenville University is known for its small class sizes and personalized attention from faculty, ensuring that students receive the support they need to succeed. The university also offers an RN-to-BSN program for registered nurses seeking to complete their degree while continuing to work.
• Accreditation: CCNE
• Tuition: Approx. $18,000 per year (undergrad)
• Programs: BSN, RN-to-BSN
• Online Options: Yes (RN-to-BSN program)

8. Spartanburg Community College Nursing Department

• Location: Spartanburg, SC
• Website: https://www.sccsc.edu
• Description: Spartanburg Community College offers a respected Associate Degree in Nursing (ADN) program that prepares students for the NCLEX-RN exam and entry into the nursing profession. The program offers a combination of classroom instruction, lab practice, and clinical rotations in hospitals and healthcare settings. SCC’s ADN program is affordable and designed to be completed in two years, making it an excellent choice for students looking to enter the workforce quickly. Additionally, Spartanburg Community College offers an RN-to-BSN program in collaboration with four-year institutions in the state, providing a seamless transition for registered nurses wishing to earn their Bachelor of Science in Nursing.
• Accreditation: ACEN
• Tuition: Approx. $3,500 per year (in-state undergrad)
• Programs: ADN, RN-to-BSN (in partnership with other universities)
• Online Options: Yes (RN-to-BSN program)

9. Trident Technical College Nursing Program

• Location: Charleston, SC
• Website: https://www.tridenttech.edu
• Description: Trident Technical College offers a competitive Associate Degree in Nursing (ADN) program that prepares students for the NCLEX-RN exam and nursing practice. The program integrates theory with practical experience through clinical rotations in local healthcare settings. Trident Technical College is known for its affordable tuition and strong community connections, providing students with a supportive learning environment. The ADN program is designed to prepare students for the demanding role of a registered nurse, with an emphasis on patient care, critical thinking, and leadership. The college also offers an RN-to-BSN pathway in partnership with universities in South Carolina.
• Accreditation: ACEN
• Tuition: Approx. $4,500 per year (in-state undergrad)
• Programs: ADN, RN-to-BSN (in partnership with other universities)
• Online Options: Yes (RN-to-BSN program)

10. Lander University Department of Nursing

• Location: Greenwood, SC
• Website: https://www.lander.edu/academics/health/nursing
• Description: Lander University offers a Bachelor of Science in Nursing (BSN) program that prepares students for the nursing profession with a strong emphasis on evidence-based practice, clinical skills, and patient-centered care. The program integrates classroom education with hands-on clinical experiences to ensure students are well-prepared for real-world nursing. Lander University’s nursing department is known for its personalized instruction and a low student-to-faculty ratio, ensuring that each student receives individual attention. The program is committed to developing nurses who are ethical, compassionate, and capable of leading in diverse healthcare settings.
• Accreditation: CCNE
• Tuition: Approx. $10,000 per year (in-state undergrad)
• Programs: BSN
• Online Options: No

How to Choose a Nursing Program in South Carolina

Selecting the right nursing program in South Carolina is a crucial decision, and this guide focuses exclusively on accredited schools, recognizing the pivotal role of accreditation in both education and career success. Key considerations encompass the total cost, including tuition and additional expenses, alongside financial aid availability. The NCLEX-RN pass rate, acceptance rate, graduation rate, program format, curriculum, and the location, especially for clinical placements, are essential factors to contemplate. This is especially pertinent if you are considering online education.

Why Become a Nurse in South Carolina

The burgeoning demand for nurses in South Carolina positions graduates of nursing schools exceptionally well for career opportunities. Despite the median salary for nurses standing at $66,050, according to the U.S. Bureau of Labor Statistics (BLS), the cost of living in South Carolina, rated at 94.8, falls below the U.S. index of 100. Additionally, being a Nurse Licensure Compact (NLC) state, South Carolina allows nurses with a local license to practice in 39 other compact states.

South Carolina boasts some of the most picturesque cities and tourist destinations in the U.S., including Myrtle Beach, Charleston, and Hilton Head Island. Whether you appreciate beaches, landscaped gardens, parks, or relish in fine Southern cuisine, South Carolina presents a plethora of attractions.

Salary and Job Outlook for Nurses in South Carolina

Both the cost of living and median annual nursing salaries in South Carolina are comparatively lower than the national figures. The median salary for a registered nurse (RN) in South Carolina is $66,050, in contrast to the national figure of $75,330. Similarly, the median salary for a nurse practitioner (NP) is $98,940, compared to $111,680 nationally.

While salaries may be lower than the national median, the cost of living is also lower. With a projected job growth of 9.4% between 2018 and 2028 and an anticipated shortage of 10,400 nurses, the demand for nurses is on the rise, contributing to an upward trend in salaries. Obtaining a degree from a nursing school in South Carolina is thus a valuable investment.

Some of Charleston’s most alluring locations also offer the highest salaries in the state. For those seeking an even higher salary, the lower Savannah South Carolina nonmetropolitan area reports an average salary of $72,920 for an RN.

Highest Paying Cities for Nurses in South Carolina

Top Paying Metropolitan Areas	Median Salary for RNs
Spartanburg	$69,260
Charleston-North Charleston	$69,130
Hilton Head Island-Bluffton-Beaufort	$67,450
Florence	$66,240
Columbia	$66,100

Source: BLS

Steps to Becoming a Nurse in South Carolina

South Carolina being an NLC state allows for practicing in the state with a license from another NLC state. However, if relocating to South Carolina, obtaining a South Carolina license becomes necessary.

RN Requirements:

Prospective RNs in South Carolina must graduate from an ADN or BSN program, pass the NCLEX-RN examination, and submit additional documentation, including a copy of identification, a notarized signature affidavit, and a 2 x 2 color passport photo form to the state board of nursing. A criminal background check is mandatory, and if the nursing school was in South Carolina, a certificate of endorsement form must be submitted. Graduates from nursing schools in other states should provide official transcripts. Detailed requirements are available on the state board of nursing website.

APRN Requirements:

For advanced practice registered nurse (APRN) licensing, candidates need an MSN or DNP and must pass the board certification examination. Additional requirements include a valid South Carolina RN license, confirmation of education and specialization, and, if intending to prescribe medications, an application for prescriptive authority, with completion of 45 hours in pharmacology coursework in the last two years, including at least 15 hours in controlled substance pharmacology.

Other Top Nursing Programs in South Carolina

Frequently Asked Questions About Nursing in South Carolina

How much are nurses paid in South Carolina?

The median salary for South Carolina nurses is $66,050, with variations based on location and experience. In the rural lower Savannah area, the average salary for an RN is $72,920, reflecting higher demand. The median salary for a nurse practitioner is $98,940.

Is South Carolina good for nursing?

While the median salary for nurses in South Carolina is below the national median, so is the cost of living. Being an NLC state, attending nursing school in South Carolina enables practicing in other NLC states. Many individuals move to South Carolina to enjoy affordable coastal living.

How many nursing schools does South Carolina have?

South Carolina boasts 25 state-approved nursing schools offering two-year ADN or four-year BSN programs. The BLS projects a 9.4% growth in nursing jobs between 2018 and 2028 in South Carolina. The U.S. Department of Health and Human Services forecasts a shortage of 10,400 nurses from 2014-2030. Given the high demand, earning a nursing degree in South Carolina proves to be a significant investment for the future.

How do I get my nursing license in South Carolina?

To obtain licensure in South Carolina, graduating from nursing school with an ADN or BSN degree, passing the NCLEX-RN exam, submitting verification of identity and eligibility to work in the U.S., and passing a criminal background check are necessary steps. The South Carolina State Board of Nursing website provides comprehensive information, including fee details.